Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CTSD | P07339 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3649345 | 0.85 | HDAC3 (0.43) | MEN1KMT2ALMNATDP1ALDH1A1 | |
| SCHEMBL4741657 | 0.82 | LMNA (0.61) | MEN1KMT2ACES2CES1L3MBTL1 | |
| SCHEMBL741751 | 0.81 | MEN1 (0.58) | MEN1KMT2ACES2CES1L3MBTL1 | |
| Acetic Acid SCHEMBL9853044 | 0.79 | MEN1 (0.53) | MEN1KMT2AL3MBTL1CTSDTDP1 | |
| Hydrochloric Acid SCHEMBL8550499 | 0.79 | MEN1 (0.56) | MEN1KMT2ACES2CES1L3MBTL1 | |
| SCHEMBL28807102 | 0.78 | MEN1 (0.53) | MEN1KMT2AL3MBTL1LMNACTSD | |
| SCHEMBL11210206 | 0.77 | TDP1 (0.44) | CES2CES1TDP1ALDH1A1TP53 | |
| SCHEMBL28038711 | 0.76 | KMT2A (0.54) | MEN1KMT2ACES2L3MBTL1LMNA | |
| SCHEMBL6140492 | 0.76 | MEN1 (0.40) | MEN1KMT2ALMNAEDNRA | |
| SCHEMBL17615223 | 0.76 | CTSB (0.38) | MEN1KMT2ACES2CES1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004022528-A2 | ARYLGLYCINE DERIVATIVES AND THEIR USE AS GLYCINE TRANSPORT INHIBITORS | NPS ALLELIX CORP. (CA) | 2004-03-18 | — | — | WO | disclosed |