Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6920376 | 0.90 | F10 (0.41) | MAOAMAOBLMNAF10 | |
| SCHEMBL6919869 | 0.89 | MAOB (0.40) | MAOAMAOBLMNAF10HTR1A | |
| SCHEMBL6918839 | 0.85 | MAOA (0.41) | MAOAMAOBALDH1A1LMNAF10 | |
| SCHEMBL3519953 | 0.84 | MAOA (0.47) | MAOAMAOBALDH1A1L3MBTL1LMNA | |
| SCHEMBL3519956 | 0.84 | MAOA (0.47) | MAOAMAOBALDH1A1L3MBTL1LMNA | |
| SCHEMBL3519113 | 0.79 | MAOB (0.46) | MAOAMAOBALDH1A1L3MBTL1LMNA | |
| SCHEMBL3519116 | 0.79 | MAOB (0.46) | MAOAMAOBALDH1A1L3MBTL1LMNA | |
| SCHEMBL3519955 | 0.78 | MAOB (0.68) | MAOAMAOBLMNAF10 | |
| SCHEMBL6919474 | 0.76 | MAOB (0.41) | MAOAMAOBLMNAF10 | |
| SCHEMBL3525099 | 0.76 | GRM2 (0.37) | ALDH1A1L3MBTL1LMNATHRBHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026848-A1 | OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPERATION AND THEIR USE AS ANTIMYCOBACTERIAL AGENTS | LUPIN LIMITED (IN) | 2004-04-01 | — | — | WO | claimed |