Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | F10 | P00742 | 6/20 | 0.39 |
| ▸ | HTR1A | P08908 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | CALML3 | P27482 | 1/20 | 0.34 |
| ▸ | SDHA | P31040 | 1/20 | 0.34 |
| ▸ | AIMP2 | Q13155 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6920376 | 0.89 | F10 (0.41) | MAOBMAOAF10LMNA | |
| SCHEMBL6918620 | 0.89 | MAOA (0.39) | MAOBMAOAF10HTR1ALMNA | |
| SCHEMBL6918839 | 0.85 | MAOA (0.41) | MAOBMAOAF10LMNAPTGS1 | |
| SCHEMBL3526403 | 0.85 | MAOB (0.47) | MAOBMAOAF10HTR1APARP1 | |
| SCHEMBL3525477 | 0.85 | MAOB (0.47) | MAOBMAOAF10HTR1APARP1 | |
| SCHEMBL3525479 | 0.80 | MAOB (0.66) | MAOBMAOAF10LMNAPTGS1 | |
| SCHEMBL3519038 | 0.79 | MAOB (0.46) | MAOBMAOAF10LMNAPTGS1 | |
| SCHEMBL3519046 | 0.79 | MAOB (0.46) | MAOBMAOAF10LMNAPTGS1 | |
| SCHEMBL6919474 | 0.77 | MAOB (0.41) | MAOBMAOAF10LMNAPTGS1 | |
| SCHEMBL6823337 | 0.76 | PARP1 (0.35) | MAOBF10HTR1APARP1AIMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026848-A1 | OXAZOLIDINONE DERIVATIVES, PROCESS FOR THEIR PREPERATION AND THEIR USE AS ANTIMYCOBACTERIAL AGENTS | LUPIN LIMITED (IN) | 2004-04-01 | — | — | WO | claimed |