SCHEMBL692491

SCHEMBL692491

CCCOC(=O)C12CC3CC(C1)CC(C(=O)OCCC)(C3)C2

nearest known ligand 0.67

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.67
ALDH1A1 P00352 3/20 0.44
LMNA P02545 4/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
MAPT P10636 2/20 0.41
PRKCA P17252 1/20 0.41
GAA P10253 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29135604 0.94 NPSR1 (0.60) NPSR1ALDH1A1LMNAL3MBTL1MEN1
SCHEMBL6863134 0.92 NPSR1 (0.57) NPSR1ALDH1A1LMNAL3MBTL1MEN1
SCHEMBL692776 0.90 NPSR1 (0.63) NPSR1ALDH1A1LMNAL3MBTL1MEN1
SCHEMBL7475995 0.89 NPSR1 (0.53) NPSR1ALDH1A1LMNAL3MBTL1MEN1
SCHEMBL691868 0.87 NPSR1 (0.60) NPSR1ALDH1A1
SCHEMBL13084353 0.87 NPSR1 (0.60) NPSR1ALDH1A1
SCHEMBL691923 0.85 NPSR1 (0.61) NPSR1ALDH1A1LMNAL3MBTL1MEN1
SCHEMBL6231540 0.84 NPSR1 (0.50) NPSR1ALDH1A1LMNAL3MBTL1MEN1
SCHEMBL29135724 0.82 NPSR1 (0.55) NPSR1ALDH1A1L3MBTL1
SCHEMBL25713906 0.82 NPSR1 (0.55) NPSR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117229160-B Triester cationic lipid compounds, compositions containing same and uses thereof 北京悦康科创医药科技股份有限公司 2024-03-08 CN disclosed
CN-117229160-A Triester cationic lipid compounds, compositions containing same and uses thereof 北京悦康科创医药科技股份有限公司 2023-12-15 CN disclosed
EP-2421904-B1 PROCATALYST COMPOSITION WITH ADAMANTANE AND METHOD GRACE W R & CO (US) 2015-06-24 EP disclosed
US-8288304-B2 Procatalyst composition with adamantane and method DOW GLOBAL TECHNOLOGIES LLC (US) 2012-10-16 US disclosed
US-8288304-B2 Procatalyst composition with adamantane and method DOW GLOBAL TECHNOLOGIES LLC (US) 2012-10-16 US disclosed
US-8288304-B2 Procatalyst composition with adamantane and method DOW GLOBAL TECHNOLOGIES LLC (US) 2012-10-16 US disclosed
EP-2421904-A1 PROCATALYST COMPOSITION WITH ADAMANTANE AND METHOD Dow Global Technologies LLC (US) 2012-02-29 EP disclosed
WO-2010123775-A1 PROCATALYST COMPOSITION WITH ADAMANTANE AND METHOD DOW GLOBAL TECHNOLOGIES INC. (US) 2010-10-28 WO disclosed
WO-2010123775-A1 PROCATALYST COMPOSITION WITH ADAMANTANE AND METHOD DOW GLOBAL TECHNOLOGIES INC. (US) 2010-10-28 WO disclosed
US-20100273966-A1 Procatalyst Composition with Adamantane and Method W. R. GRACE & CO.-CONN. 2010-10-28 US disclosed
US-20100273966-A1 Procatalyst Composition with Adamantane and Method W. R. GRACE & CO.-CONN. 2010-10-28 US disclosed
US-20100273966-A1 Procatalyst Composition with Adamantane and Method W. R. GRACE & CO.-CONN. 2010-10-28 US disclosed