Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21348115 | 0.70 | — | — | |
| SCHEMBL11530230 | 0.69 | MEN1 (0.33) | MEN1GABRA1CYP2C19GABRB2KMT2A | |
| SCHEMBL24510333 | 0.65 | MEN1 (0.32) | MEN1GABRA1CYP2C19GABRB2KMT2A | |
| SCHEMBL6824902 | 0.64 | PNMT (0.37) | — | |
| SCHEMBL8487410 | 0.63 | L3MBTL1 (0.41) | CYP2C19 | |
| SCHEMBL279754 | 0.61 | — | — | |
| SCHEMBL23177091 | 0.60 | CRBN (0.36) | MEN1GABRA1CYP2C19GABRB2KMT2A | |
| SCHEMBL11749187 | 0.58 | — | — | |
| SCHEMBL10715 | 0.58 | — | — | |
| SCHEMBL4298137 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014909-A1 | FUSED TETRAHYDROPYRIDINE DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |