Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | JUN | P05412 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6710351 | 0.95 | MAPT (0.38) | MAPTMEN1KMT2AMAPK8MAPK9 | |
| SCHEMBL6713410 | 0.91 | PKM (0.40) | MAPTMEN1KMT2AMAPK8MAPK9 | |
| SCHEMBL6707757 | 0.90 | KMT2A (0.49) | MEN1KMT2AMAPK8MAPK9HDAC1 | |
| SCHEMBL6713331 | 0.89 | PARP14 (0.38) | MAPTMAPK8MAPK9TP53JUN | |
| SCHEMBL6711647 | 0.86 | MAPT (0.41) | MAPTMEN1KMT2AMAPK8MAPK9 | |
| SCHEMBL6714324 | 0.86 | PARP14 (0.42) | MAPTMEN1KMT2ABACE1ALDH1A1 | |
| SCHEMBL6710064 | 0.86 | ALDH1A1 (0.40) | MAPTMEN1KMT2ATP53HDAC1 | |
| SCHEMBL6710320 | 0.85 | PARP14 (0.39) | MAPTMEN1KMT2ATP53RXFP1 | |
| SCHEMBL6711793 | 0.84 | CSNK1D (0.45) | MAPTMEN1KMT2ATP53HDAC1 | |
| SCHEMBL6708888 | 0.84 | KDM4E (0.43) | MAPTMEN1KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |