Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25419165 | 0.70 | LRRK2 (0.32) | — | |
| SCHEMBL18270917 | 0.68 | NQO1 (0.35) | — | |
| SCHEMBL28874743 | 0.60 | KMT2A (0.51) | — | |
| SCHEMBL9139255 | 0.60 | TAAR1 (0.42) | — | |
| SCHEMBL11317826 | 0.59 | GRM5 (0.33) | GRM5 | |
| SCHEMBL28634711 | 0.59 | ACMSD (0.47) | — | |
| SCHEMBL29501710 | 0.59 | SMN1; SMN2 (0.48) | — | |
| SCHEMBL27460313 | 0.59 | MAPT (0.36) | — | |
| SCHEMBL23093951 | 0.59 | THRB (0.40) | — | |
| SCHEMBL9123636 | 0.58 | NQO1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1470102-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | Applied Research Systems ARS Holding N.V. (AN) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003064376-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-08-07 | — | — | WO | disclosed |