Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 6/20 | 0.57 |
| ▸ | TAS1R1 | Q7RTX1 | 6/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 5/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2410701 | 1.00 | TAS1R3 (0.57) | TAS1R3TAS1R1ALDH1A1LMNATHRB | |
| SCHEMBL2409768 | 0.83 | ALDH1A1 (0.77) | TAS1R3TAS1R1ALDH1A1LMNATHRB | |
| SCHEMBL2407811 | 0.83 | ALDH1A1 (0.77) | TAS1R3TAS1R1ALDH1A1LMNATHRB | |
| SCHEMBL5792707 | 0.82 | TAS1R3 (0.54) | TAS1R3TAS1R1ALDH1A1LMNATHRB | |
| SCHEMBL445823 | 0.82 | TAS1R3 (0.54) | TAS1R3TAS1R1ALDH1A1LMNATHRB | |
| SCHEMBL3942752 | 0.82 | HPGD (0.53) | TAS1R3TAS1R1ALDH1A1LMNATHRB | |
| SCHEMBL2406514 | 0.81 | HDAC1 (0.61) | TAS1R3TAS1R1ALDH1A1LMNATHRB | |
| SCHEMBL2406940 | 0.81 | HDAC1 (0.61) | TAS1R3TAS1R1ALDH1A1LMNATHRB | |
| SCHEMBL2407984 | 0.80 | ALDH1A1 (0.55) | TAS1R3TAS1R1ALDH1A1LMNATHRB | |
| SCHEMBL704600 | 0.79 | TAS1R3 (0.80) | TAS1R3TAS1R1ALDH1A1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011106632-A1 | SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2011-09-01 | — | — | WO | disclosed |