Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | GFER | P55789 | 1/20 | 0.51 |
| ▸ | GPR27 | Q9NS67 | 3/20 | 0.51 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.45 |
| ▸ | HSD17B13 | Q7Z5P4 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6348358 | 0.80 | METAP2 (0.71) | METAP2HPGDMAPTGFERGPR27 | |
| SCHEMBL19083016 | 0.75 | METAP2 (1.00) | METAP2LMNA | |
| SCHEMBL1030477 | 0.75 | GFER (0.83) | HPGDMAPTGFERMEN1KMT2A | |
| SCHEMBL2831972 | 0.73 | CA12 (0.68) | HPGDMAPTGFERNHERF1MEN1 | |
| SCHEMBL6831830 | 0.73 | CA12 (0.68) | HPGDMAPTGFERNHERF1MEN1 | |
| SCHEMBL6349460 | 0.71 | MEN1 (0.60) | METAP2MAPTGFERGPR27MEN1 | |
| SCHEMBL13028459 | 0.71 | GFER (0.77) | HPGDMAPTGFERMEN1KMT2A | |
| SCHEMBL6352083 | 0.71 | METAP2 (0.67) | METAP2MAPTGFERGPR27MEN1 | |
| SCHEMBL28170795 | 0.70 | MAPT (0.79) | HPGDMAPTGFERMEN1KMT2A | |
| SCHEMBL15480530 | 0.70 | HDAC6 (0.74) | HPGDMAPTGFERMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018414-A2 | ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |