Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5152438 | 0.88 | MEN1 (0.72) | MEN1KMT2AMAPTHPGDPOLB | |
| SCHEMBL5152843 | 0.83 | MEN1 (0.75) | MEN1KMT2AMAPTHPGDPOLB | |
| SCHEMBL19306397 | 0.78 | KMT2A (0.78) | MEN1KMT2AMAPTHPGDPOLB | |
| SCHEMBL5155073 | 0.76 | MEN1 (0.55) | MEN1KMT2AMAPTHPGDPOLB | |
| SCHEMBL5156863 | 0.74 | MEN1 (0.53) | MEN1KMT2AMAPTHTR7 | |
| SCHEMBL19306513 | 0.74 | MEN1 (0.71) | MEN1KMT2AMAPTHPGDCYP2C9 | |
| SCHEMBL19305954 | 0.73 | MEN1 (0.81) | MEN1KMT2AMAPTHPGDPOLB | |
| SCHEMBL5155057 | 0.71 | KMT2A (0.67) | MEN1KMT2AMAPTPOLBCYP2C9 | |
| SCHEMBL5694454 | 0.71 | MAOA (0.47) | ALDH1A1HTR7 | |
| SCHEMBL5150098 | 0.71 | MEN1 (0.57) | MEN1KMT2AMAPTHPGDPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004017965-A1 | 1,3-THIAZOLIN-4-ONES AS THERAPEUTIC COMPOUNDS IN THE TREATMENT OF PAIN | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-03-04 | — | — | WO | disclosed |