Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 2/20 | 0.47 |
| ▸ | OPRD1 | P41143 | 14/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6655122 | 1.00 | P2RX7 (0.47) | P2RX7OPRD1TSHROPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL6657006 | 0.87 | OPRD1 (0.54) | P2RX7OPRD1TSHROPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL6657016 | 0.87 | OPRD1 (0.54) | P2RX7OPRD1TSHROPRM1OPRK1 | |
| Hydrochloric Acid SCHEMBL6657004 | 0.87 | OPRD1 (0.54) | P2RX7OPRD1TSHROPRM1OPRK1 | |
| SCHEMBL6924540 | 0.87 | OPRD1 (0.47) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6657412 | 0.87 | OPRD1 (0.47) | OPRD1OPRM1OPRK1 | |
| SCHEMBL6653601 | 0.85 | P2RX7 (0.54) | P2RX7OPRD1TSHROPRM1OPRK1 | |
| SCHEMBL6653585 | 0.85 | P2RX7 (0.54) | P2RX7OPRD1TSHROPRM1OPRK1 | |
| SCHEMBL6653593 | 0.85 | P2RX7 (0.54) | P2RX7OPRD1TSHROPRM1OPRK1 | |
| SCHEMBL6656899 | 0.83 | P2RX7 (0.55) | P2RX7OPRD1TSHROPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6514975-B1 | Tetrazoles as selective agonists for the delta opioid receptor | PFIZER INC | 2003-02-04 | — | — | US | disclosed |