SCHEMBL5037951

SCHEMBL5037951

CCCCN(CCC)c1nc(N)nc(N(c2ccc(OC)c(Cl)c2)C2CCN(C)CC2)n1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
EHMT2 Q96KQ7 8/20 0.47
EHMT1 Q9H9B1 8/20 0.47
MEN1 O00255 1/20 0.46
LMNA P02545 1/20 0.46
KMT2A Q03164 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
PGR P06401 2/20 0.39
HRH4 Q9H3N8 2/20 0.38
DRD2 P14416 2/20 0.35
HTR7 P34969 2/20 0.35
HTR6 P50406 2/20 0.35
CRHR1 P34998 1/20 0.35
QPCT Q16769 1/20 0.33
QPCTL Q9NXS2 1/20 0.33
HTR2A P28223 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6919803 0.80 EHMT2 (0.45) EHMT2EHMT1PGRHRH4
SCHEMBL4836307 0.76 EHMT2 (0.47) EHMT2EHMT1MEN1LMNAKMT2A
SCHEMBL4874024 0.76 HRH4 (0.57) HRH4DRD2HTR7HTR6HTR2A
SCHEMBL5553578 0.75 RECQL (0.39) MEN1LMNAKMT2AL3MBTL1HRH4
SCHEMBL5556168 0.72 SMN1; SMN2 (0.41) MEN1LMNAKMT2AL3MBTL1HRH4
SCHEMBL14454103 0.72 BCL6 (0.46) EHMT2EHMT1MEN1LMNAKMT2A
SCHEMBL6608704 0.72 UBE2M (0.36) EHMT2EHMT1MEN1KMT2APGR
SCHEMBL4829448 0.72 EHMT2 (0.56) EHMT2EHMT1MEN1LMNAKMT2A
SCHEMBL5033412 0.71 EHMT2 (0.38) EHMT2EHMT1LMNAPGRHRH4
SCHEMBL6609401 0.71 EHMT2 (0.41) EHMT2EHMT1PGRHRH4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7332490-B2 Methods and compositions of novel triazine compounds REDDY US THERAPEUTICS, INC. (US) 2008-02-19 US disclosed
US-20070004729-A1 Methods and compositions of novel triazine compounds REDDY US THERAPEUTICS, INC. 2007-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070004729-A1 Methods and compositions of novel triazine compounds AREG, TGFB1, PTGIS EHMT2 2905/4885EHMT1 2811/4885MEN1 4761/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.