Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EHMT2 | Q96KQ7 | 6/20 | 0.41 |
| ▸ | EHMT1 | Q9H9B1 | 6/20 | 0.41 |
| ▸ | PGR | P06401 | 2/20 | 0.41 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.40 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.38 |
| ▸ | SPIN1 | Q9Y657 | 1/20 | 0.37 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | KMT5A | Q9NQR1 | 2/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | FGFR3 | P22607 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.34 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.34 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6919803 | 0.86 | EHMT2 (0.45) | EHMT2EHMT1PGRSLC2A1HRH4 | |
| SCHEMBL5033412 | 0.77 | EHMT2 (0.38) | EHMT2EHMT1PGRSLC2A1HRH4 | |
| SCHEMBL4839209 | 0.76 | EHMT2 (0.50) | EHMT2EHMT1KMT5ASMN1; SMN2CYP2C19 | |
| SCHEMBL6237774 | 0.75 | EHMT2 (0.45) | EHMT2EHMT1SLC2A1HRH4SPIN1 | |
| SCHEMBL6016980 | 0.74 | SMN1; SMN2 (0.38) | SMN1; SMN2FGFR3FGFR1FGFR2FGFR4 | |
| SCHEMBL4832263 | 0.74 | SLC2A1 (0.37) | EHMT2EHMT1SLC2A1HRH4SPIN1 | |
| SCHEMBL4874024 | 0.72 | HRH4 (0.57) | HRH4 | |
| SCHEMBL6016881 | 0.72 | MAPK1 (0.36) | EHMT2EHMT1SLC2A1HRH4SPIN1 | |
| SCHEMBL4835516 | 0.72 | BCL6 (0.44) | EHMT2EHMT1 | |
| SCHEMBL5037951 | 0.71 | EHMT2 (0.47) | EHMT2EHMT1PGRHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1436266-A4 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS INC (US) | 2004-12-22 | — | — | EP | claimed |
| EP-1436266-A2 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | Reddy US Therapeutics, Inc. (US) | 2004-07-14 | — | — | EP | claimed |
| WO-2003024926-A2 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS, INC. (US) | 2003-03-27 | — | — | WO | claimed |