Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.49 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.49 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6929296 | 0.90 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPTGLACYP3A4 | |
| SCHEMBL6827768 | 0.88 | ALDH1A1 (0.57) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL3069113 | 0.88 | ALDH1A1 (0.60) | ALDH1A1LMNAMAPTGLACYP3A4 | |
| SCHEMBL6925728 | 0.88 | ALDH1A1 (0.56) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL3066690 | 0.87 | ALDH1A1 (0.55) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL6924871 | 0.87 | ALDH1A1 (0.55) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL6923782 | 0.87 | ALDH1A1 (0.55) | ALDH1A1LMNAKMT2AMEN1MAPT | |
| SCHEMBL6925877 | 0.86 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPTGLACYP3A4 | |
| SCHEMBL6925065 | 0.85 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPTGLACYP3A4 | |
| SCHEMBL6827869 | 0.84 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPTGLACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073619-A2 | CCR8 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-09-02 | — | — | WO | claimed |
| WO-2004073619-A2 | CCR8 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-09-02 | — | — | WO | disclosed |