Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6827768 | 0.95 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPTGAAALOX15 | |
| SCHEMBL6925728 | 0.94 | ALDH1A1 (0.56) | ALDH1A1LMNAMAPTGAAALOX15 | |
| SCHEMBL3066690 | 0.93 | ALDH1A1 (0.55) | ALDH1A1LMNAMAPTGAAALOX15 | |
| SCHEMBL6924871 | 0.93 | ALDH1A1 (0.55) | ALDH1A1LMNAMAPTGAAALOX15 | |
| SCHEMBL6923782 | 0.93 | ALDH1A1 (0.55) | ALDH1A1LMNAMAPTGAAALOX15 | |
| SCHEMBL3069113 | 0.93 | ALDH1A1 (0.60) | ALDH1A1LMNAMAPTGAAALOX15 | |
| SCHEMBL6919941 | 0.90 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPTGAAALOX15 | |
| SCHEMBL6831335 | 0.89 | ALDH1A1 (0.67) | ALDH1A1LMNAMAPTGAAALOX15 | |
| SCHEMBL6925877 | 0.89 | ALDH1A1 (0.58) | ALDH1A1LMNAMAPTGAAALOX15 | |
| SCHEMBL6925065 | 0.88 | ALDH1A1 (0.57) | ALDH1A1LMNAMAPTGAAALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073619-A2 | CCR8 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-09-02 | — | — | WO | disclosed |