Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F9 | P00740 | 8/20 | 0.48 |
| ▸ | F11 | P03951 | 3/20 | 0.48 |
| ▸ | F7 | P08709 | 3/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | G6PD | P11413 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | AURKA | O14965 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1232626 | 0.90 | F9 (0.48) | F9F11F7CYP2C9F10 | |
| SCHEMBL9607754 | 0.90 | F9 (0.41) | F9F11F7CYP2C9F10 | |
| SCHEMBL9607621 | 0.90 | F9 (0.64) | F9F11F7CYP2C9F10 | |
| SCHEMBL9607622 | 0.89 | F9 (0.65) | F9F11F7CYP2C9F10 | |
| SCHEMBL6918626 | 0.72 | HTR2A (0.46) | F9F11F7CYP2C9F10 | |
| SCHEMBL1231149 | 0.69 | F9 (0.65) | F9F11F7F10TP53 | |
| SCHEMBL6918055 | 0.69 | F9 (0.63) | F9F11F7CYP2C9F10 | |
| SCHEMBL1231102 | 0.69 | ABCG2 (0.57) | F9TP53MEN1KMT2AGBA1 | |
| SCHEMBL9607759 | 0.69 | MEN1 (0.52) | F9F11F7CYP2C9F10 | |
| SCHEMBL9607763 | 0.69 | MEN1 (0.52) | F9F11F7CYP2C9F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011017296-A1 | 4, 5, 6-TRISUBSTITUTED PYRIMIDINE DERIVATIVES AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2011-02-10 | — | — | WO | disclosed |