Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.42 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3557435 | 0.84 | HPGD (0.47) | MEN1KMT2APTGS2AKR1C3AKR1C2 | |
| SCHEMBL6440279 | 0.82 | POLB (0.47) | KDM4EMAPTHSD17B10LMNATSHR | |
| SCHEMBL6921207 | 0.78 | KDM4E (0.44) | MEN1KMT2APTGS2KDM4EAKR1C3 | |
| SCHEMBL3558589 | 0.74 | MAPT (0.51) | MEN1KMT2AKDM4EAKR1C3AKR1C2 | |
| SCHEMBL18052964 | 0.73 | MAPT (0.50) | MEN1KMT2AKDM4EAKR1C3AKR1C2 | |
| SCHEMBL10876035 | 0.72 | AKR1C3 (0.76) | MEN1KMT2APTGS2KDM4EAKR1C3 | |
| SCHEMBL6920234 | 0.71 | P2RX4 (0.45) | PTGS2MAPTHTTCYP1A2CYP2D6 | |
| SCHEMBL6817298 | 0.70 | LMNA (0.61) | MEN1KMT2APTGS2KDM4EAKR1C3 | |
| SCHEMBL31336577 | 0.70 | PTGS2 (0.44) | MEN1KMT2APTGS2KDM4EAKR1C3 | |
| SCHEMBL3553237 | 0.69 | KDM4E (0.44) | MEN1KMT2AKDM4ECYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | disclosed |