⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10916892 | 0.92 | TSHR (0.38) | — | |
| SCHEMBL15121126 | 0.90 | TSHR (0.40) | — | |
| SCHEMBL9477891 | 0.90 | TSHR (0.40) | — | |
| SCHEMBL1235840 | 0.90 | TSHR (0.40) | — | |
| SCHEMBL10491876 | 0.90 | TSHR (0.40) | — | |
| SCHEMBL9787912 | 0.90 | TSHR (0.40) | — | |
| SCHEMBL8763241 | 0.85 | — | — | |
| SCHEMBL9478548 | 0.82 | — | — | |
| SCHEMBL14908 | 0.82 | — | — | |
| SCHEMBL13584591 | 0.80 | FDPS (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054845-A1 | MACROCYCIC COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF | SIONNA THERAPEUTICS (US) | 2024-03-14 | — | — | WO | disclosed |
| US-20230269999-A1 | ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES | UNIVERSAL DISPLAY CORPORATION (US) | 2023-08-24 | — | — | US | disclosed |
| WO-2023107863-A1 | HETEROCYCLIC COMPOUNDS AS KIT KINASE INHIBITORS | DECIPHERA PHARMACEUTICALS, LLC (US) | 2023-06-15 | — | — | WO | disclosed |
| CN-111051239-B | Method for producing cyclic phosphonitrile chloride trimer | 大塚化学株式会社 | 2022-12-23 | — | — | CN | disclosed |
| EP-2348023-B9 | Heteroaryl substituted pyrrolo[2,3-b]pyridines and pyrrolo[2,3-b]pyrimidines as Janus kinase inhibitors | INCYTE HOLDINGS CORP (US) | 2017-03-08 | — | — | EP | disclosed |
| CN-101765593-A | 2-iminoisothiazole derivatives as cannabinoid receptor ligands | ABBOTT LAB | 2010-06-30 | — | — | CN | disclosed |
| WO-2003099810-A2 | RADIOPHARMACEUTICALS FOR IMAGING INFECTION AND INFLAMMATION | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2003-12-04 | — | — | WO | disclosed |
| EP-1347784-A2 | SIMULTANEOUS DUAL ISOTOPE IMAGING OF CARDIAC PERFUSION AND CARDIAC INFLAMMATION | Bristol-Myers Squibb Pharma Company (US) | 2003-10-01 | — | — | EP | disclosed |
| WO-2002036173-A2 | SIMULTANEOUS DUAL ISOTOPE IMAGING OF CARDIAC PERFUSION AND CARDIAC INFLAMMATION | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2002-05-10 | — | — | WO | disclosed |
| EP-0999856-A2 | RADIOPHARMACEUTICALS FOR IMAGING INFECTION AND INFLAMMATION | Du Pont Pharmaceuticals Company (US) | 2000-05-17 | — | — | EP | disclosed |
| WO-1998015295-A2 | RADIOPHARMACEUTICALS FOR IMAGING INFECTION AND INFLAMMATION | DUPONT PHARMACEUTICALS COMPANY (US) | 1998-04-16 | — | — | WO | disclosed |
| US-4243681-A | VASODILATION, ANTISPASMODIC AGENTS; ANTICOAGULANTS | MEAD JOHNSON & COMPANY (US) | 1981-01-06 | — | — | US | disclosed |
| US-4147805-A | VASODILATION, ANTISPASMODIC AGENTS, ANTICOAGULATNS, ADRENOLYTIC AGENTS | MEAD JOHNSON & COMPANY (US) | 1979-04-03 | — | — | US | disclosed |