Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 10/20 | 0.35 |
| ▸ | GGPS1 | O95749 | 7/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10916892 | 0.87 | TSHR (0.38) | FDPSGGPS1SMPD1TSHR | |
| SCHEMBL9787912 | 0.85 | TSHR (0.40) | FDPSGGPS1SMPD1TSHR | |
| SCHEMBL10491876 | 0.85 | TSHR (0.40) | FDPSGGPS1SMPD1TSHR | |
| SCHEMBL9477891 | 0.85 | TSHR (0.40) | FDPSGGPS1SMPD1TSHR | |
| SCHEMBL15121126 | 0.85 | TSHR (0.40) | FDPSGGPS1SMPD1TSHR | |
| SCHEMBL1235840 | 0.85 | TSHR (0.40) | FDPSGGPS1SMPD1TSHR | |
| SCHEMBL6920148 | 0.80 | — | — | |
| SCHEMBL808750 | 0.80 | FDPS (0.48) | FDPSGGPS1SMPD1TSHR | |
| SCHEMBL9374930 | 0.78 | FDPS (0.50) | FDPSGGPS1SMPD1TSHR | |
| SCHEMBL2346921 | 0.78 | FDPS (0.50) | FDPSGGPS1SMPD1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090312315-A1 | PAI-1 INHIBITOR | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2009-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312315-A1 | PAI-1 INHIBITOR | SERPINC1, SERPINE1, SERPINH1 | FDPS 3333/4885GGPS1 3100/4885SMPD1 2929/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.