Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | DHODH | Q02127 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 2/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | F9 | P00740 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6919662 | 0.81 | ABCG2 (0.55) | ABCG2ADORA2AADORA1KDM4EKDM1A | |
| SCHEMBL1232774 | 0.73 | F9 (0.53) | MEN1KMT2AABCG2KDM4EDHODH | |
| SCHEMBL21982029 | 0.67 | ABCG2 (0.62) | ABCG2 | |
| SCHEMBL6919145 | 0.67 | F9 (0.42) | MEN1KMT2AABCG2ADORA2AADORA1 | |
| SCHEMBL1231102 | 0.66 | ABCG2 (0.57) | MEN1KMT2AABCG2ADORA2AADORA1 | |
| SCHEMBL9607749 | 0.66 | ABCG2 (0.50) | MEN1KMT2AABCG2KDM4EKDM1A | |
| SCHEMBL29165766 | 0.65 | MMP3 (0.41) | CA12CA1CA2CA9PTGS2 | |
| SCHEMBL6919146 | 0.64 | KDM4E (0.44) | MEN1KMT2AABCG2ADORA2AADORA1 | |
| SCHEMBL21728479 | 0.62 | L3MBTL1 (0.44) | MEN1KMT2AABCG2ADORA2AADORA1 | |
| SCHEMBL23020098 | 0.62 | ADORA1 (0.34) | MEN1KMT2AABCG2ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011017296-A1 | 4, 5, 6-TRISUBSTITUTED PYRIMIDINE DERIVATIVES AS FACTOR IXA INHIBITORS | SCHERING CORPORATION (US) | 2011-02-10 | — | — | WO | disclosed |