Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 16/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6899145 | 0.87 | GABRP (0.37) | TACR1GAAKDM4EMAPT | |
| SCHEMBL6902335 | 0.87 | TACR1 (0.38) | TACR1GAA | |
| SCHEMBL6904039 | 0.81 | ALDH1A1 (0.32) | TACR1 | |
| SCHEMBL6918811 | 0.79 | ATM (0.34) | TACR1KDM4EMAPT | |
| SCHEMBL8658515 | 0.75 | MYC (0.40) | TACR1GAAKDM4E | |
| SCHEMBL6918745 | 0.75 | HSD17B10 (0.35) | TACR1KDM4E | |
| SCHEMBL6906060 | 0.74 | ALDH1A1 (0.39) | TACR1GAAPOLBMAPT | |
| SCHEMBL6424614 | 0.73 | TACR1 (0.47) | TACR1KDM4E | |
| SCHEMBL6907264 | 0.70 | USP2 (0.41) | TACR1POLBMAPT | |
| SCHEMBL6906160 | 0.69 | TACR1 (0.35) | TACR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004111000-A2 | PIPERIDYL DERIVATIVES AND THEIR USE AS TACHYKININ ANTAGONISTS | ASTELLAS PHARMA INC. (JP) | 2004-12-23 | — | — | WO | disclosed |