Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 11/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | F11 | P03951 | 1/20 | 0.36 |
| ▸ | CFD | P00746 | 3/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.36 |
| ▸ | F10 | P00742 | 5/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.36 |
| ▸ | F12 | P00748 | 3/20 | 0.36 |
| ▸ | F7 | P08709 | 3/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6919276 | 0.92 | F2 (0.38) | F2CYP3A4ALDH1A1F11CFD | |
| SCHEMBL6918602 | 0.89 | F2 (0.42) | F2CYP3A4ALDH1A1F11CFD | |
| SCHEMBL6918596 | 0.89 | F2 (0.42) | F2CYP3A4ALDH1A1F11CFD | |
| SCHEMBL6077326 | 0.87 | ALDH1A1 (0.49) | F2ALDH1A1PRSS1F10PRSS2 | |
| SCHEMBL6922167 | 0.85 | F2 (0.52) | F2CYP3A4F11CFDPRSS1 | |
| SCHEMBL6920452 | 0.84 | SCN9A (0.36) | F2PRSS1F10PRSS2PRSS3 | |
| SCHEMBL6917198 | 0.83 | F2 (0.52) | F2CYP3A4F11CFDPRSS1 | |
| SCHEMBL6919688 | 0.82 | F2 (0.52) | F2CYP3A4F11CFDPRSS1 | |
| SCHEMBL6921244 | 0.81 | F2 (0.47) | F2CYP3A4CFDPRSS1F10 | |
| SCHEMBL6919764 | 0.81 | F2 (0.47) | F2CYP3A4F11CFDPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004032834-A2 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2004-04-22 | — | — | WO | disclosed |