Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL547196 | 0.86 | ESR1 (0.42) | RAB9ANPC1ESR1ESR2L3MBTL1 | |
| SCHEMBL3657210 | 0.85 | RAB9A (0.45) | RAB9ANPC1ESR1ESR2KMT2A | |
| SCHEMBL19301952 | 0.81 | RAB9A (0.59) | RAB9ANPC1ESR1ESR2KMT2A | |
| SCHEMBL6918007 | 0.78 | RAB9A (0.41) | RAB9ANPC1KMT2AMEN1MAPK9 | |
| SCHEMBL6813021 | 0.78 | ESR1 (0.47) | RAB9ANPC1ESR1ESR2KMT2A | |
| SCHEMBL3420124 | 0.76 | RAB9A (0.37) | RAB9ANPC1ESR1ESR2KMT2A | |
| SCHEMBL6445254 | 0.73 | RAB9A (0.38) | RAB9ANPC1KMT2AMEN1L3MBTL1 | |
| SCHEMBL22221860 | 0.73 | RAB9A (0.53) | RAB9ANPC1ESR1ESR2KMT2A | |
| SCHEMBL24317809 | 0.71 | RAB9A (0.46) | RAB9ANPC1ESR1ESR2KMT2A | |
| SCHEMBL19301933 | 0.69 | RAB9A (0.46) | RAB9ANPC1ESR1ESR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018460-A1 | AMINO METHYL IMIDAZOLES AS C5A RECEPTOR MODULATORS | NEUROGEN CORPORATION (US) | 2004-03-04 | — | — | WO | disclosed |