Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ALOX15B | O15296 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3420124 | 0.81 | RAB9A (0.37) | RAB9ANPC1MAPTKMT2AMEN1 | |
| SCHEMBL6920489 | 0.78 | RAB9A (0.42) | RAB9ANPC1MAPK9KMT2AALDH1A1 | |
| SCHEMBL6653812 | 0.78 | MAPT (0.38) | NPC1CYP3A4MAPTMAPK9CYP2C19 | |
| SCHEMBL1299021 | 0.75 | MAPT (0.43) | NPC1CYP3A4MAPTMAPK9CYP2C19 | |
| SCHEMBL20012845 | 0.74 | NPC1 (0.49) | RAB9ANPC1CYP3A4MAPTCYP2C19 | |
| SCHEMBL3657210 | 0.73 | RAB9A (0.45) | RAB9ANPC1CYP3A4MAPTMAPK9 | |
| SCHEMBL18393413 | 0.69 | CYP3A4 (0.38) | CYP3A4MAPTMAPK9CYP2C19TRPM8 | |
| SCHEMBL17495240 | 0.69 | TDP1 (0.40) | RAB9ANPC1MAPTHPGDSMN1; SMN2 | |
| SCHEMBL6529538 | 0.68 | MAPT (0.65) | NPC1CYP3A4MAPTMAPK9CYP2C19 | |
| SCHEMBL5156297 | 0.68 | MAPT (0.65) | NPC1CYP3A4MAPTMAPK9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018460-A1 | AMINO METHYL IMIDAZOLES AS C5A RECEPTOR MODULATORS | NEUROGEN CORPORATION (US) | 2004-03-04 | — | — | WO | disclosed |