Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | CCKBR | P32239 | 7/20 | 0.50 |
| ▸ | XIAP | P98170 | 6/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.41 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.41 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.41 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.41 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.41 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4414990 | 0.99 | ALDH1A1 (0.60) | ALDH1A1CCKBRXIAP | |
| SCHEMBL8022024 | 0.84 | CCKBR (0.46) | ALDH1A1CCKBRXIAPPSEN1PSEN2 | |
| SCHEMBL6917930 | 0.83 | XIAP (0.47) | ALDH1A1CCKBRXIAPPSEN1PSEN2 | |
| Hydrochloric Acid SCHEMBL4415323 | 0.83 | XIAP (0.45) | ALDH1A1CCKBRXIAPPSEN1PSEN2 | |
| Hydrochloric Acid SCHEMBL4412033 | 0.82 | XIAP (0.46) | ALDH1A1CCKBRXIAPPSEN1PSEN2 | |
| SCHEMBL6912415 | 0.80 | PSEN1 (0.56) | CCKBRXIAPPSEN1PSEN2APH1B | |
| Hydrochloric Acid SCHEMBL4411847 | 0.79 | PSEN1 (0.55) | CCKBRXIAPPSEN1PSEN2APH1B | |
| SCHEMBL8020336 | 0.78 | ALDH1A1 (0.52) | ALDH1A1CCKBRXIAPPSEN1PSEN2 | |
| SCHEMBL4416841 | 0.78 | PSEN1 (0.52) | ALDH1A1CCKBRXIAPPSEN1PSEN2 | |
| SCHEMBL4416543 | 0.78 | ALDH1A1 (0.51) | ALDH1A1CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1093372-A4 | CYCLIC AMINO ACID COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING $g(b)-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS | ELAN PHARM INC (US) | 2004-09-29 | — | — | EP | disclosed |
| EP-1093372-A1 | CYCLIC AMINO ACID COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING $g(b)-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS | Elan Pharmaceuticals, Inc. (US) | 2001-04-25 | — | — | EP | disclosed |
| WO-1999066934-A1 | CYCLIC AMINO ACID COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING β-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS | ELAN PHARMACEUTICALS, INC. (US) | 1999-12-29 | — | — | WO | disclosed |
| EP-0951466-A2 | CYCLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS, PHARMACEUTICAL COMPOSITIONS COMPRISING SAME, AND METHODS FOR INHIBITING BETA-AMYLOID PEPTIDE RELEASE AND/OR ITS SYNTHESIS BY USE OF SUCH COMPOUNDS | Elan Pharmaceuticals, Inc. (US) | 1999-10-27 | — | — | EP | disclosed |
| WO-1998028268-A2 | CYCLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS AS β-AMYLOID PEPTIDE RELEASE INHIBITORS | ELAN PHARMACEUTICALS, INC. (US) | 1998-07-02 | — | — | WO | disclosed |