Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9430413 | 0.98 | HRH3 (0.43) | HRH3ALDH1A1TSHRL3MBTL1MAPT | |
| SCHEMBL9077800 | 0.78 | HRH3 (0.46) | HRH3ALDH1A1L3MBTL1MAPTCYP1A2 | |
| SCHEMBL1637997 | 0.75 | MEN1 (0.44) | HRH3ALDH1A1TSHRL3MBTL1MAPT | |
| SCHEMBL16172041 | 0.74 | LTA4H (0.49) | HRH3ALDH1A1L3MBTL1 | |
| SCHEMBL9075801 | 0.74 | HRH3 (0.41) | HRH3ALDH1A1MAPTCYP1A2MAPK1 | |
| SCHEMBL9313742 | 0.73 | HRH3 (0.42) | HRH3ALDH1A1TSHRL3MBTL1MAPT | |
| SCHEMBL172955 | 0.73 | HRH3 (0.56) | HRH3MAPTCYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL439729 | 0.73 | HRH3 (0.56) | HRH3MAPTCYP1A2MAPK1SMN1; SMN2 | |
| SCHEMBL21348734 | 0.72 | HRH3 (0.50) | HRH3L3MBTL1MAPTCYP1A2MAPK1 | |
| SCHEMBL15709972 | 0.72 | PTPN1 (0.54) | HRH3ALDH1A1CYP1A2MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2951188-B1 | PHOSPHORUS LIGANDS AND METHOD FOR THE SELECTIVE RUTHENIUM-CATALYZED HYDROAMINOMETHYLATION OF OLEFINS | EVONIK DEGUSSA GMBH (DE) | 2017-05-10 | — | — | EP | disclosed |
| EP-2951188-B1 | PHOSPHORUS LIGANDS AND METHOD FOR THE SELECTIVE RUTHENIUM-CATALYZED HYDROAMINOMETHYLATION OF OLEFINS | EVONIK DEGUSSA GMBH (DE) | 2017-05-10 | — | — | EP | disclosed |
| EP-2951188-A1 | PHOSPHORUS LIGANDS AND METHOD FOR THE SELECTIVE RUTHENIUM-CATALYZED HYDROAMINOMETHYLATION OF OLEFINS | Evonik Degussa GmbH (DE) | 2015-12-09 | — | — | EP | disclosed |
| WO-2014118038-A1 | PHOSPHORUS LIGANDS AND METHOD FOR THE SELECTIVE RUTHENIUM-CATALYZED HYDROAMINOMETHYLATION OF OLEFINS | EVONIK INDUSTRIES AG (DE) | 2014-08-07 | — | — | WO | disclosed |
| WO-2003101931-A2 | PREPARATION OF 4-(N, N-DISUBSTITUTEDAMINO) BUTYRALDEHYDE ACETALS | NATCO PHARMA LIMITED (IN) | 2003-12-11 | — | — | WO | disclosed |