Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 10/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6922172 | 0.91 | L3MBTL1 (0.42) | GRM5TDP1L3MBTL1RAB9ANPC1 | |
| SCHEMBL9995144 | 0.85 | GRM5 (0.41) | GRM5TDP1L3MBTL1RAB9ANPC1 | |
| SCHEMBL12059799 | 0.84 | BCL2A1 (0.39) | TDP1L3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6921520 | 0.84 | L3MBTL1 (0.54) | TDP1L3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL20755644 | 0.83 | ALDH1A1 (0.36) | TDP1L3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6921662 | 0.83 | MEN1 (0.54) | TDP1L3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL6922869 | 0.82 | GRM5 (0.44) | GRM5TDP1L3MBTL1RAB9ANPC1 | |
| SCHEMBL2053268 | 0.82 | L3MBTL1 (0.41) | GRM5TDP1L3MBTL1RAB9ANPC1 | |
| SCHEMBL2053312 | 0.81 | L3MBTL1 (0.35) | TDP1L3MBTL1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL9994522 | 0.81 | GRM5 (0.40) | GRM5TDP1L3MBTL1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011075699-A2 | COMPOUNDS FOR TREATING DISORDERS MEDIATED BY METABOTROPIC GLUTAMATE RECEPTOR 5, AND METHODS OF USE THEREOF | SUNOVION PHARMACEUTICALS INC. (US) | 2011-06-23 | — | — | WO | disclosed |