Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29368373 | 0.78 | OPRL1 (0.44) | RPS6KA3OPRL1 | |
| SCHEMBL28680491 | 0.78 | OPRL1 (0.44) | RPS6KA3OPRL1 | |
| SCHEMBL743476 | 0.78 | RPS6KA3 (0.33) | RPS6KA3OPRL1 | |
| SCHEMBL28680489 | 0.78 | OPRL1 (0.44) | RPS6KA3OPRL1 | |
| SCHEMBL319870 | 0.69 | AOC3 (0.33) | RPS6KA3 | |
| SCHEMBL1911019 | 0.69 | AOC3 (0.33) | RPS6KA3 | |
| SCHEMBL19849321 | 0.69 | AOC3 (0.33) | RPS6KA3 | |
| SCHEMBL14435392 | 0.66 | — | — | |
| SCHEMBL14902619 | 0.66 | AOC1 (0.31) | — | |
| SCHEMBL14902618 | 0.66 | AOC1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011061168-A1 | ARYL-PYRIDINE DERIVATIVES AS ALDOSTERONE SYNTHASE INHIBITORS | NOVARTIS AG (CH) | 2011-05-26 | — | — | WO | disclosed |