Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 19/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 19/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22443481 | 0.84 | THRB (0.43) | HCRTR1HCRTR2 | |
| SCHEMBL17979225 | 0.84 | THRB (0.43) | HCRTR1HCRTR2 | |
| SCHEMBL9381558 | 0.84 | THRB (0.43) | HCRTR1HCRTR2 | |
| SCHEMBL6821194 | 0.78 | HCRTR1 (0.45) | HCRTR1HCRTR2DPP4 | |
| SCHEMBL13232246 | 0.78 | HCRTR2 (0.35) | HCRTR1HCRTR2 | |
| SCHEMBL22443722 | 0.78 | HCRTR1 (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL22443719 | 0.78 | HCRTR1 (0.48) | HCRTR1HCRTR2 | |
| SCHEMBL14784304 | 0.76 | HCRTR1 (0.34) | HCRTR1HCRTR2 | |
| SCHEMBL14778971 | 0.76 | HCRTR1 (0.34) | HCRTR1HCRTR2 | |
| SCHEMBL15906111 | 0.74 | HCRTR1 (0.42) | HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037813-A1 | PYRROLIDIN-2-ON DERIVATIVES AS EP4 RECEPTOR AGONISTS | MERCK FROSST CANADA & CO. (CA) | 2004-05-06 | — | — | WO | disclosed |