SCHEMBL6921257

SCHEMBL6921257

O=C1c2ccccc2-c2ncnc3cccc1c23.c1ccc2cc3c(ccc4ncncc43)cc2c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.42
NPC1 O15118 2/20 0.39
RAB9A P51151 2/20 0.39
MAPT P10636 3/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
KDM4E B2RXH2 1/20 0.37
HSP90AA1 P07900 1/20 0.37
HSP90AB1 P08238 1/20 0.37
HPGD P15428 1/20 0.37
HTT P42858 1/20 0.37
APEX1 P27695 1/20 0.36
CES1 P23141 1/20 0.35
EGFR P00533 1/20 0.35
MAOB P27338 1/20 0.34
PIK3CD O00329 2/20 0.34
PIK3CA P42336 2/20 0.34
PIK3CB P42338 1/20 0.34
MTOR P42345 1/20 0.34
PIK3CG P48736 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Anthraquinone SCHEMBL20262985 0.87 EGFR (0.41) MAOANPC1RAB9AMEN1KMT2A
SCHEMBL57892 0.78 EGFR (0.50) NPC1RAB9AMAPTMEN1KMT2A
SCHEMBL460367 0.78 MAOA (0.56) MAOANPC1RAB9AMAPTMEN1
Anthraquinone SCHEMBL11386415 0.68 EGFR (0.74) MAOANPC1RAB9AMAPTMEN1
SCHEMBL11209540 0.68 EGFR (0.44) NPC1RAB9AMAPTMEN1KMT2A
SCHEMBL4141797 0.67 RAF1 (0.40) HSP90AA1EGFRPIK3CDPIK3CA
SCHEMBL11704158 0.67 EGFR (0.42) NPC1RAB9AMAPTMEN1KMT2A
SCHEMBL8128384 0.66 EGFR (0.53) NPC1RAB9AMAPTKMT2AKDM4E
SCHEMBL28401294 0.65 EGFR (0.44) NPC1RAB9AMAPTMEN1KMT2A
SCHEMBL1758755 0.65 MAOA (0.53) MAOANPC1RAB9AMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0445926-A2 Organic materials having sulfonamido linked poly(oxyalkylene) moieties and their preparation MILLIKEN RESEARCH CORPORATION (US) 1991-09-11 EP claimed
US-20040195552-A1 useful as powders or pellets for incorporation into a variety of thermoplastic resins; diacidic anthraquinone compounds WEAVER MAX ALLEN (US) 2004-10-07 US disclosed
US-6776930-B2 POLYMER BONDED TO DYE EASTMAN KODAK COMPANY 2004-08-17 US disclosed
US-20010023938-A1 Polymer bonded to dye ALLEN MAX (US) 2001-09-27 US disclosed
US-6197223-B1 REACTING DIACIDIC MONOMER HAVING FORMULA H--A--H, COMPRISING 1 TO 100 MOLE % OF LIGHT-ABSORBING MONOMER HAVING A LIGHT ABSORPTION MAXIMUM BETWEEN 300 NM AND 1200 NM AND 99-0 MOLE % OF A NON-LIGHT ABSORBING MONOMER WITH ORGANIC COMPOUND EASTMAN CHEMICAL COMPANY 2001-03-06 US disclosed
EP-0445926-B1 Organic materials having sulfonamido linked poly(oxyalkylene) moieties and their preparation MILLIKEN RES CORP (US) 1996-08-21 EP disclosed
US-5240464-A Organic materials having sulfonamido linked poly(oxyalkylene) moieties and their preparation MILLIKEN RESEARCH CORPORATION (US) 1993-08-31 US disclosed
EP-0445926-A2 Organic materials having sulfonamido linked poly(oxyalkylene) moieties and their preparation MILLIKEN RESEARCH CORPORATION (US) 1991-09-11 EP disclosed