Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GALR1 | P47211 | 2/20 | 0.49 |
| ▸ | GSK3A | P49840 | 2/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.48 |
| ▸ | PAK4 | O96013 | 1/20 | 0.47 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4840101 | 0.90 | GALR1 (0.61) | KCNH3MAPTLMNAGALR1GSK3A | |
| SCHEMBL4832671 | 0.88 | KCNH3 (0.57) | KCNH3MAPTLMNAGALR1GSK3A | |
| SCHEMBL4838923 | 0.84 | GALR1 (0.67) | GALR1SMN1; SMN2L3MBTL1 | |
| SCHEMBL6234629 | 0.80 | GALR1 (0.48) | MAPTGALR1ALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL6235647 | 0.80 | GALR1 (0.47) | KCNH3LMNAGALR1TNK2ALDH1A1 | |
| SCHEMBL16453398 | 0.80 | TNK2 (0.76) | KCNH3MAPTTNK2PAK4PAK1 | |
| Hydrochloric Acid SCHEMBL16445903 | 0.79 | TNK2 (0.75) | KCNH3MAPTLMNATNK2PAK4 | |
| SCHEMBL5551996 | 0.79 | GALR1 (0.47) | MAPTLMNAGALR1TSHRBLM | |
| SCHEMBL14302189 | 0.78 | KCNH3 (0.53) | KCNH3MAPTLMNATNK2PAK4 | |
| SCHEMBL5032177 | 0.78 | KDM4E (0.40) | KCNH3MAPTLMNAGALR1GSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026844-A9 | METHODS AND COMPOSITIONS OF NOVEL TRIAZINE COMPOUNDS | REDDY US THERAPEUTICS INC (US) | 2004-11-11 | — | — | WO | claimed |