SCHEMBL6921574

SCHEMBL6921574

CCCCCC(C#N)(C#N)Cc1ccc(Sc2ccc(C)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MCL1 Q07820 1/20 0.33
KCNH2 Q12809 3/20 0.32
MLYCD O95822 1/20 0.32
CNR2 P34972 1/20 0.31
PKM P14618 1/20 0.31
TSHR P16473 1/20 0.31
HSD17B10 Q99714 1/20 0.31
EBP Q15125 1/20 0.30
SIGMAR1 Q99720 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6921577 0.83 AR (0.40) EBPSIGMAR1
SCHEMBL6918166 0.78 PSMD14 (0.40) TSHRHSD17B10EBPSIGMAR1HPGD
SCHEMBL6839460 0.77 MCL1 (0.34) MCL1MLYCD
SCHEMBL6835187 0.75 ESR1 (0.36) CNR2TSHRHSD17B10EBPSIGMAR1
SCHEMBL6920878 0.75 CA1 (0.37) TSHRHSD17B10EBPSIGMAR1
SCHEMBL6921008 0.73 KMT2A (0.42) HSD17B10
SCHEMBL29727587 0.72 ATM (0.42) EBPSIGMAR1
SCHEMBL6920964 0.72 KCNH2 (0.45) KCNH2TSHR
SCHEMBL6821404 0.72 TSHR (0.40) TSHRHSD17B10
SCHEMBL22488774 0.72 ESR1 (0.50) KCNH2TSHRHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1385377-A1 PESTICIDE COMPOSITION COMPRISING MALONONITRILE COMPOUNDS SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2004-02-04 EP disclosed
WO-2002089579-A1 PESTICIDE COMPOSITION COMPRISING MALONONITRILE COMPOUNDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-11-14 WO disclosed