Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMD14 | O00487 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | RAD52 | P43351 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | EBP | Q15125 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6835187 | 0.84 | ESR1 (0.36) | TSHRHSD17B10EBPSIGMAR1LMNA | |
| SCHEMBL6920878 | 0.81 | CA1 (0.37) | TSHRHSD17B10EBPSIGMAR1ESR1 | |
| SCHEMBL6821404 | 0.81 | TSHR (0.40) | TSHRHSD17B10LMNAALDH1A1MAPT | |
| SCHEMBL6919697 | 0.80 | KIF11 (0.38) | FFAR1 | |
| SCHEMBL4657442 | 0.80 | LOXL2 (0.39) | DPP4ESR1ESR2 | |
| SCHEMBL6840018 | 0.79 | ESR1 (0.37) | LMNAESR1ESR2ALDH1A1HTT | |
| SCHEMBL6921008 | 0.79 | KMT2A (0.42) | HSD17B10LMNAALDH1A1MAPTKMT2A | |
| SCHEMBL4658834 | 0.78 | MAOA (0.33) | HSD17B10DPP4ESR1ESR2ALDH1A1 | |
| SCHEMBL29727587 | 0.78 | ATM (0.42) | EBPSIGMAR1LMNAHTTKMT2A | |
| SCHEMBL6921574 | 0.78 | MCL1 (0.33) | HPGDTSHRHSD17B10EBPSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1385377-A1 | PESTICIDE COMPOSITION COMPRISING MALONONITRILE COMPOUNDS | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002089579-A1 | PESTICIDE COMPOSITION COMPRISING MALONONITRILE COMPOUNDS | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2002-11-14 | — | — | WO | disclosed |