⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9819151 | 0.77 | ALDH1A1 (0.62) | — | |
| SCHEMBL325076 | 0.77 | ALDH1A1 (0.62) | — | |
| Allylthiourea SCHEMBL27561760 | 0.75 | TSHR (0.82) | — | |
| Iodide SCHEMBL8715119 | 0.74 | ALDH1A1 (0.59) | — | |
| SCHEMBL36968 | 0.74 | — | — | |
| SCHEMBL290485 | 0.74 | — | — | |
| SCHEMBL29987 | 0.74 | — | — | |
| SCHEMBL9482524 | 0.72 | — | — | |
| SCHEMBL4027523 | 0.72 | — | — | |
| SCHEMBL10695320 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014070774-A1 | METHODS OF GENERATING BETA-LACTAMASE RESISTANT CARBAPENEM COMPOUNDS | SOUTHERN METHODIST UNIVERSITY (US) | 2014-05-08 | — | — | WO | claimed |
| US-20140121192-A1 | METHODS OF GENERATING BETA-LACTAMASE RESISTANT CARBAPENEM COMPOUNDS | SOUTHERN METHODIST UNIVERSITY (US) | 2014-05-01 | — | — | US | claimed |
| EP-2167081-B1 | BACTERICIDAL ANTI-MRSA ACTIVE PHARMACEUTICAL COMPOSITION CONTAINING CARBAPENEMS | PFAENDLER HANS RUDOLF (DE) | 2013-06-26 | — | — | EP | claimed |
| EP-1740551-B9 | HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF AS AN MMP-13 INHIBITOR | TAKEDA PHARMACEUTICAL (JP) | 2013-01-16 | — | — | EP | claimed |
| EP-1740551-B1 | HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF AS AN MMP-13 INHIBITOR | TAKEDA PHARMACEUTICAL (JP) | 2012-09-12 | — | — | EP | claimed |
| EP-1953148-B1 | HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL (JP) | 2012-02-29 | — | — | EP | claimed |
| US-20100173887-A1 | BACTERICIDAL ANTI-MRSA ACTIVE PHARMACEUTICAL COMPOSITION CONTAINING CARBAPENEMS | PFAENDLER HANS RUDOLF | 2010-07-08 | — | — | US | claimed |
| EP-2167081-A1 | BACTERICIDAL ANTI-MRSA ACTIVE PHARMACEUTICAL COMPOSITION CONTAINING CARBAPENEMS | Pfaendler, Hans Rudolf (DE) | 2010-03-31 | — | — | EP | claimed |
| EP-2126083-A1 | HOOGSTEEN-TYPE TRIPLEX FORMATION OF PYRENE LABELLED PROBES FOR NUCLEIC ACID DETECTION IN FLUORESCENCE ASSAY | Pedersen, Erik Bjerregaard (DK) | 2009-12-02 | — | — | EP | claimed |
| WO-2008141764-A1 | BACTERICIDAL ANTI-MRSA ACTIVE PHARMACEUTICAL COMPOSITION CONTAINING CARBAPENEMS | PFAENDLER HANS RUDOLF (DE) | 2008-11-27 | — | — | WO | claimed |
| EP-0548790-B1 | (1'S)-Hydroxyalkyloxapenem-3-carboxylic acids and their use as beta-lactamase inhibitors | LILLY CO ELI (US) | 1996-05-01 | — | — | EP | claimed |
| US-5461060-A | Antiretroviral activity | MITSUBISHI KASEI CORPORATION (JP) | 1995-10-24 | — | — | US | claimed |
| EP-0362622-B1 | Use of stable oxapenem-3-carboxylic acids for the manufacture of beta-lactamase inhibiting medicaments | LILLY CO ELI (US) | 1995-03-29 | — | — | EP | claimed |
| EP-0301394-B1 | STABLE OXAPENEM-3-CARBOXYLIC ACIDS | Pfaendler, Hans Rudolf, Prof. Dr. (DE) | 1993-10-06 | — | — | EP | claimed |
| EP-0548790-A1 | (1'S)-Hydroxyalkyloxapenem-3-carboxylic acids and their use as beta-lactamase inhibitors | ELI LILLY AND COMPANY (US) | 1993-06-30 | — | — | EP | claimed |
| US-5108747-A | STABLE OXPENEM-3-CARBOXYLIC ACIDS AS BETA-LACTAMASE INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-04-28 | — | — | US | claimed |
| US-5096899-A | Nonhydrolyzing oxapenicillins | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-17 | — | — | US | claimed |
| EP-0420763-A2 | 6-Substituted acyclopyrimidine nucleoside derivatives and antiviral agent containing the same as active ingredient thereof | Mitsubishi Chemical Corporation (JP) | 1991-04-03 | — | — | EP | claimed |
| EP-0000640-B1 | TETRAHYDRO-S-TRIAZINE THIONES, PROCESS FOR THEIR PREPARATION AND ACARICIDAL COMPOSITIONS CONTAINING THEM. | Pfizer Limited (GB) | 1981-06-03 | — | — | EP | claimed |
| EP-0000640-A1 | Tetrahydro-s-triazine thiones, process for their preparation and acaricidal compositions containing them. | Pfizer Limited (GB) | 1979-02-07 | — | — | EP | claimed |