SCHEMBL6921696

SCHEMBL6921696

CCC(C)[C@H](NC(=O)Nc1cc(Cl)ccc1Cl)C(=O)N(CC(=O)NO)CC1CCCC1

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
LMNA P02545 1/20 0.40
GAA P10253 1/20 0.40
TSHR P16473 1/20 0.40
FPR2 P25090 3/20 0.38
CYP2C19 P33261 1/20 0.37
MEN1 O00255 2/20 0.36
POLB P06746 2/20 0.36
KMT2A Q03164 2/20 0.36
TP53 P04637 1/20 0.36
MAPT P10636 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TAS1R3 Q7RTX0 2/20 0.36
TAS1R1 Q7RTX1 2/20 0.36
TRPV1 Q8NER1 1/20 0.35
NPSR1 Q6W5P4 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6822312 1.00 ALDH1A1 (0.40) ALDH1A1LMNAGAATSHRFPR2
SCHEMBL6822314 1.00 ALDH1A1 (0.40) ALDH1A1LMNAGAATSHRFPR2
SCHEMBL6822382 0.92 ALDH1A1 (0.41) ALDH1A1LMNAGAATSHRCYP2C19
SCHEMBL6825361 0.90 ALDH1A1 (0.41) ALDH1A1LMNAGAATSHRCYP2C19
SCHEMBL6824960 0.85 ANPEP (0.45) ALDH1A1LMNAGAATSHRTRPV1
SCHEMBL6825505 0.85 RAB9A (0.44) ALDH1A1LMNAGAATSHRTAS1R3
SCHEMBL6825256 0.84 CYP2C19 (0.38) ALDH1A1LMNAGAATSHRCYP2C19
SCHEMBL6822349 0.83 ALDH1A1 (0.40) ALDH1A1LMNAGAATSHRCYP2C19
SCHEMBL6825325 0.83 MAPK1 (0.43) ALDH1A1LMNAGAATSHRTAS1R3
SCHEMBL6825910 0.82 MEN1 (0.37) ALDH1A1LMNAGAATSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004087643-A1 DEFORMYLASE INHIBITOR, PROCESS FOR PREPARING THE SAME, AND ANTIBACTERIAL COMPOSITION COMPRISING THE SAME PROMEDITECH INC. (KR) 2004-10-14 WO disclosed