Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | VDR | P11473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7747822 | 0.85 | GAA (0.51) | MEN1KMT2AMAPTGAAATM | |
| SCHEMBL13477405 | 0.82 | MEN1 (0.48) | MEN1KMT2AMAPTGAAATM | |
| SCHEMBL13140601 | 0.82 | MEN1 (0.52) | MEN1KMT2AMAPTGAAATM | |
| SCHEMBL1557163 | 0.82 | MEN1 (0.48) | MEN1KMT2AMAPTGAAATM | |
| SCHEMBL13140550 | 0.79 | MEN1 (0.46) | MEN1KMT2AMAPTGAAATM | |
| SCHEMBL13140535 | 0.78 | MRGPRX4 (0.47) | MEN1KMT2AMAPTGAAATM | |
| SCHEMBL13140631 | 0.77 | ALDH1A1 (0.43) | MEN1KMT2AMAPTGAAATM | |
| SCHEMBL1072206 | 0.76 | ALDH1A1 (0.58) | MEN1KMT2AMAPTGAAALDH1A1 | |
| SCHEMBL2219482 | 0.76 | ALDH1A1 (0.58) | MEN1KMT2AMAPTGAAATM | |
| SCHEMBL5558132 | 0.76 | PDE10A (0.50) | MEN1KMT2AMAPTGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004099185-A1 | 2-CYANOPYRROLIDINE DERIVATIVES AND THEIR USE AS DPP-IV INHIBITORS | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2004-11-18 | — | — | WO | disclosed |