Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | PNLIP | P16233 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 6/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | LCLAT1 | Q6UWP7 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6713639 | 0.92 | TP53 (0.42) | MAPTGBA1GAARXFP1PNLIP | |
| SCHEMBL6709883 | 0.91 | GAA (0.47) | MAPTGAARXFP1MEN1KMT2A | |
| SCHEMBL6708672 | 0.85 | NPC1 (0.46) | MAPTGAARXFP1POLBTP53 | |
| SCHEMBL6711397 | 0.84 | TP53 (0.41) | MAPTGAARXFP1MEN1KMT2A | |
| SCHEMBL6707769 | 0.83 | MEN1 (0.48) | MAPTGAARXFP1MEN1KMT2A | |
| SCHEMBL6713914 | 0.82 | RXFP1 (0.44) | MAPTGAARXFP1MEN1KMT2A | |
| SCHEMBL6710253 | 0.82 | TP53 (0.43) | MAPTRXFP1MEN1KMT2APOLB | |
| SCHEMBL6713838 | 0.82 | GRIK1 (0.41) | MAPTPOLBTP53LMNA | |
| SCHEMBL6712433 | 0.81 | GRIK1 (0.42) | MAPTGAAMEN1KMT2APOLB | |
| SCHEMBL6713903 | 0.81 | GAA (0.43) | MAPTGAARXFP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004018461-A2 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |