Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | G6PD | P11413 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.40 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.40 |
| ▸ | CDK4 | P11802 | 1/20 | 0.39 |
| ▸ | CCND1 | P24385 | 1/20 | 0.39 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6709883 | 0.94 | GAA (0.47) | NPC1RAB9AL3MBTL1POLBG6PD | |
| SCHEMBL6714076 | 0.91 | KMT2A (0.41) | NPC1RAB9AL3MBTL1POLBALDH1A1 | |
| SCHEMBL6713838 | 0.90 | GRIK1 (0.41) | POLBALDH1A1GRIK1MAPTTP53 | |
| SCHEMBL6707994 | 0.89 | CETP (0.43) | CETPPOLBG6PDGRIK1SERPINE1 | |
| SCHEMBL6710078 | 0.89 | ALDH1A1 (0.37) | NPC1RAB9AL3MBTL1POLBALDH1A1 | |
| SCHEMBL6710410 | 0.88 | USP2 (0.43) | POLBGRIK1MAPTTP53LMNA | |
| SCHEMBL6709861 | 0.88 | GRIK1 (0.41) | L3MBTL1POLBALDH1A1GRIK1TP53 | |
| SCHEMBL6710141 | 0.88 | GRIK1 (0.44) | PRSS12GRIK1SERPINE1RXFP1 | |
| SCHEMBL6709877 | 0.87 | GRIK1 (0.43) | NPC1RAB9APOLBALDH1A1GRIK1 | |
| SCHEMBL6712543 | 0.87 | GRIK1 (0.43) | POLBGRIK1MAPTRXFP1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142981-A1 | Antibacterial benzoic acid derivatives | GABRD, PHB1, GABBR1 | NPC1 3891/4885RAB9A 3732/4885L3MBTL1 2013/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.