⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL692227 | 1.00 | — | — | |
| Cysteine SCHEMBL27977650 | 0.79 | PTGS1 (0.94) | — | |
| SCHEMBL16690306 | 0.79 | — | — | |
| Cysteine SCHEMBL30525215 | 0.79 | — | — | |
| SCHEMBL12015634 | 0.77 | — | — | |
| Cysteine SCHEMBL28172077 | 0.77 | — | — | |
| SCHEMBL13594047 | 0.77 | — | — | |
| SCHEMBL358881 | 0.75 | — | — | |
| SCHEMBL5555288 | 0.75 | — | — | |
| Cysteine SCHEMBL4289403 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106659687-A | Delayed release compositions of linaclotide | 硬木药品公司 | 2017-05-10 | — | — | CN | claimed |
| CN-104053449-A | Treatments for gastrointestinal disorders | IRONWOOD PHARMACEUTICALS INC | 2014-09-17 | — | — | CN | claimed |
| JP-2004501784-A | — | — | 2004-01-22 | — | — | JP | claimed |
| EP-1297010-A2 | BIOELASTOMER NANOMACHINES AND BIOSENSORS | BIOELASTICS RESEARCH, LTD. (US) | 2003-04-02 | — | — | EP | claimed |
| US-20020068304-A1 | Bioelastomer nanomachines and biosensors | BIOELASTICS RESEARCH, LTD. | 2002-06-06 | — | — | US | claimed |
| WO-2002000686-A2 | BIOELASTOMER NANOMACHINES AND BIOSENSORS | BIOELASTICS RESEARCH, LTD. (US) | 2002-01-03 | — | — | WO | claimed |
| US-6335176-B1 | REAGENT IS SUCCINIMIDYL MOIETY LINKED TO KINASE SUBSTRATE; CAN BE LINKED TO FREE PRIMARY OR SECONDARY AMINE IN COMPOUND TO BE PHOSPHORYLATED | PHARMACOPEIA, INC. | 2002-01-01 | — | — | US | claimed |
| WO-2025101983-A1 | NON-STEROIDAL ISONITRILE BINDING COMPOUNDS OF CYTOCHROME P450 SUBTYPES | BRANDEIS UNIVERSITY (US) | 2025-05-15 | — | — | WO | disclosed |
| US-20240368212-A1 | SELECTIVE ISONITRILE INHIBITORS OF CYTOCHROME P450 SUBTYPES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2024-11-07 | — | — | US | disclosed |
| EP-4392036-A1 | SELECTIVE ISONITRILE INHIBITORS OF CYTOCHROME P450 SUBTYPES | Brandeis University (US) | 2024-07-03 | — | — | EP | disclosed |
| WO-2023028205-A1 | SELECTIVE ISONITRILE INHIBITORS OF CYTOCHROME P450 SUBTYPES | BRANDEIS UNIVERSITY (US) | 2023-03-02 | — | — | WO | disclosed |
| US-20220263033-A1 | ETCHING PROCESS | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2022-08-18 | — | — | US | disclosed |
| CN-110475564-A | With the modification of Linaclotide or delayed release preparation treatment irritable bowel syndrome method | IRONWOOD PHARMACEUTICALS INC | 2019-11-19 | — | — | CN | disclosed |
| WO-1991003493-A1 | BI-OR TRISPECIFIC (FAB)3 OR (FAB)4 CONJUGATES | THE UNIVERSITY OF SOUTHAMPTON (GB) | 1991-03-21 | — | — | WO | disclosed |
| US-4451394-A | Dodecapeptides preventing glucose and triglyceride assimilation | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-05-29 | — | — | US | disclosed |
| US-4440904-A | CYCLIC POLYPEPTIDES; RESIN PEPTIDES; ANTIULCER AGENTS; HORMONE INHIBITORS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1984-04-03 | — | — | US | disclosed |
| US-4328135-A | Octapeptides lowering growth hormone | AMERICAN HOME PRODUCTS CORPORATION (US) | 1982-05-04 | — | — | US | disclosed |
| US-4282143-A | Octapeptides lowering growth hormone | AMERICAN HOME PRODUCTS CORPORATION (US) | 1981-08-04 | — | — | US | disclosed |
| US-4225472-A | Truncated somatostatin analogs | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-09-30 | — | — | US | disclosed |
| US-4185010-A | SOMATOSTATIN ANALOGUES; ANTIDIABETIC AND HYPOGLYCEMIC AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1980-01-22 | — | — | US | disclosed |