Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 11/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7065300 | 0.81 | MAPT (0.69) | GRM4MAPTLMNATP53MEN1 | |
| SCHEMBL6828985 | 0.81 | SMN1; SMN2 (0.51) | GRM4MAPTCA1CA2TP53 | |
| SCHEMBL7193667 | 0.78 | KMT2A (0.55) | MAPTMEN1KMT2A | |
| SCHEMBL6829211 | 0.77 | GRM4 (0.56) | ALOX15GRM4MAPTLMNATP53 | |
| SCHEMBL6829771 | 0.76 | NPC1 (0.50) | MAPTLMNAMEN1KMT2A | |
| SCHEMBL6829063 | 0.76 | MEN1 (0.60) | MAPTLMNATP53MEN1KMT2A | |
| SCHEMBL6829196 | 0.75 | GAA (0.57) | GRM4MAPTLMNATP53MEN1 | |
| SCHEMBL6829504 | 0.73 | SMN1; SMN2 (0.55) | GRM4MAPTLMNATP53MEN1 | |
| SCHEMBL20138986 | 0.72 | HPGD (0.47) | ALOX15GRM4MAPTKMT2A | |
| SCHEMBL20138984 | 0.72 | HPGD (0.47) | ALOX15GRM4MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004037808-A1 | 2 - SUBSTITUTED HETEROCYCLIC COMPOUNDS AND ANTITUMOR COMPOSITION COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2004-05-06 | — | — | WO | disclosed |