Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2C | P18825 | 13/20 | 0.91 |
| ▸ | ADRA2A | P08913 | 12/20 | 0.91 |
| ▸ | ADRA2B | P18089 | 10/20 | 0.72 |
| ▸ | KDM1A | O60341 | 8/20 | 0.72 |
| ▸ | GLA | P06280 | 1/20 | 0.72 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.72 |
| ▸ | RECQL | P46063 | 1/20 | 0.72 |
| ▸ | BLM | P54132 | 1/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.72 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.69 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.69 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.69 |
| ▸ | DRD1 | P21728 | 1/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.69 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.69 |
| ▸ | HTR1D | P28221 | 1/20 | 0.69 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.69 |
| ▸ | HTR7 | P34969 | 1/20 | 0.69 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.69 |
| ▸ | HRH1 | P35367 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7127774 | 0.95 | ADRA2A (1.00) | ADRA2CADRA2AADRA2BKDM1AGLA | |
| SCHEMBL6821471 | 0.89 | ADRA2A (0.94) | ADRA2CADRA2AADRA2BKDM1AGLA | |
| SCHEMBL6922102 | 0.87 | ADRA2A (0.92) | ADRA2CADRA2AADRA2BKDM1AGLA | |
| SCHEMBL6821547 | 0.85 | ADRA2A (1.00) | ADRA2CADRA2AADRA2BKDM1AGLA | |
| SCHEMBL6821566 | 0.85 | ADRA2C (0.84) | ADRA2CADRA2AADRA2BKDM1AGLA | |
| SCHEMBL1664525 | 0.84 | KDM1A (1.00) | ADRA2CADRA2AADRA2BKDM1AGLA | |
| SCHEMBL6818670 | 0.83 | ADRA2A (0.77) | ADRA2CADRA2AADRA2BKDM1AGLA | |
| SCHEMBL7130095 | 0.82 | ADRA2A (1.00) | ADRA2CADRA2AADRA2BKDM1AGLA | |
| SCHEMBL7123693 | 0.82 | ADRA2A (1.00) | ADRA2CADRA2AADRA2BKDM1AGLA | |
| SCHEMBL6818639 | 0.81 | ADRA2C (0.70) | ADRA2CADRA2AADRA2BKDM1AGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004067513-A1 | ANTAGONISTS FOR ALPHA-2 ADRENOCEPTORS | OY JUVANTIA PHARMA LTD (FI) | 2004-08-12 | — | — | WO | claimed |
| WO-2004067513-A1 | ANTAGONISTS FOR ALPHA-2 ADRENOCEPTORS | OY JUVANTIA PHARMA LTD (FI) | 2004-08-12 | — | — | WO | disclosed |