Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | MEN1 | O00255 | 3/20 | 0.66 |
| ▸ | MAPT | P10636 | 3/20 | 0.66 |
| ▸ | GAA | P10253 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29818694 | 0.82 | MEN1 (0.57) | KMT2AMEN1MAPTGAAL3MBTL1 | |
| SCHEMBL13140583 | 0.80 | MEN1 (0.55) | KMT2AMEN1MAPTGAAL3MBTL1 | |
| SCHEMBL9694491 | 0.80 | MEN1 (1.00) | KMT2AMEN1MAPTGAAL3MBTL1 | |
| SCHEMBL1598728 | 0.79 | ALDH1A1 (0.42) | KMT2AMEN1MAPTPOLBATM | |
| SCHEMBL770153 | 0.77 | CASP3 (0.54) | KMT2AMEN1MAPTGAAALDH1A1 | |
| SCHEMBL10914237 | 0.76 | MEN1 (0.76) | KMT2AMEN1MAPTGAAL3MBTL1 | |
| SCHEMBL6918907 | 0.76 | KMT2A (0.56) | KMT2AMEN1MAPTGAAATM | |
| SCHEMBL29367470 | 0.76 | KMT2A (0.74) | KMT2AMEN1MAPTGAAL3MBTL1 | |
| SCHEMBL6524461 | 0.76 | KMT2A (0.74) | KMT2AMEN1MAPTGAAL3MBTL1 | |
| SCHEMBL10912874 | 0.75 | MEN1 (0.73) | KMT2AMEN1MAPTGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004099185-A1 | 2-CYANOPYRROLIDINE DERIVATIVES AND THEIR USE AS DPP-IV INHIBITORS | FUJISAWA PHARMACEUTICAL CO. LTD. (JP) | 2004-11-18 | — | — | WO | disclosed |