SCHEMBL6922837

SCHEMBL6922837

COC(=O)C(CCCCCCCCCCC(C(C)=O)C(=O)OC)C(C)=O

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ZDHHC7 Q9NXF8 1/20 0.47
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
FAAH O00519 1/20 0.37
ABCB1 P08183 1/20 0.37
TRPV1 Q8NER1 1/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
USP2 O75604 1/20 0.36
LMNA P02545 1/20 0.36
ALDH1A1 P00352 1/20 0.33
MME P08473 1/20 0.33
MGAM O43451 1/20 0.32
GAA P10253 1/20 0.32
SI P14410 1/20 0.32
MGAM2 Q2M2H8 1/20 0.32
TSHR P16473 1/20 0.32
PLA2G2A P14555 1/20 0.32
BIRC2 Q13490 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3289939 0.92 ZDHHC7 (0.59) ZDHHC7CA1CA2FAAHABCB1
SCHEMBL11352057 0.92 ZDHHC7 (0.59) ZDHHC7CA1CA2FAAHABCB1
SCHEMBL7641997 0.92 ZDHHC7 (0.42) ZDHHC7CA1CA2FAAHABCB1
SCHEMBL8586333 0.92 ZDHHC7 (0.42) ZDHHC7CA1CA2FAAHABCB1
SCHEMBL7645423 0.92 ZDHHC7 (0.59) ZDHHC7CA1CA2FAAHABCB1
SCHEMBL7751074 0.92 ZDHHC7 (0.59) ZDHHC7CA1CA2FAAHABCB1
SCHEMBL7635540 0.92 ZDHHC7 (0.59) ZDHHC7CA1CA2FAAHABCB1
SCHEMBL6925379 0.90 PAOX (0.41) ZDHHC7CA1CA2FAAHABCB1
SCHEMBL7642070 0.90 ZDHHC7 (0.41) ZDHHC7CA1CA2FAAHABCB1
SCHEMBL7634831 0.90 ZDHHC7 (0.44) ZDHHC7CA1CA2FAAHABCB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1156029-B1 Derivatives of acetoacetic acid, their process of preparation and their use BASF AG (DE) 2003-06-18 EP disclosed
US-6515154-B2 Acetoacetic acid derivatives, process for their preparation and their use BASF AKTIENGESELLSCHAFT (DE) 2003-02-04 US disclosed
US-20010056195-A1 Acetoacetic acid derivatives, process for their preparation and their use BASF AKTIENGESELLSCHAFT (DE) 2001-12-27 US disclosed
EP-1156029-A1 Derivatives of acetoacetic acid, their process of preparation and their use BASF AKTIENGESELLSCHAFT (DE) 2001-11-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010056195-A1 Acetoacetic acid derivatives, process for their preparation and their use ACMSD, MLYCD, HADHB ZDHHC7 2169/4885CA1 743/4885CA2 798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.