Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 4/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | STS | P08842 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6830911 | 0.98 | ALDH1A1 (0.56) | ALDH1A1LMNAGAAL3MBTL1NPC1 | |
| SCHEMBL6830792 | 0.95 | ALDH1A1 (0.59) | ALDH1A1LMNAGAAL3MBTL1NPC1 | |
| SCHEMBL3066507 | 0.90 | KMT2A (0.47) | ALDH1A1LMNAGAAL3MBTL1NPC1 | |
| SCHEMBL6926861 | 0.88 | KMT2A (0.46) | ALDH1A1LMNAGAAL3MBTL1NPC1 | |
| SCHEMBL6928532 | 0.85 | KMT2A (0.47) | ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL6827768 | 0.85 | ALDH1A1 (0.57) | ALDH1A1LMNAGAAL3MBTL1KMT2A | |
| SCHEMBL6830931 | 0.85 | KMT2A (0.48) | ALDH1A1LMNAGAAL3MBTL1NPC1 | |
| SCHEMBL3063905 | 0.84 | ALDH1A1 (0.56) | ALDH1A1LMNAGAANPC1KMT2A | |
| SCHEMBL6923769 | 0.83 | KMT2A (0.47) | ALDH1A1LMNAKMT2AMEN1STS | |
| SCHEMBL6925728 | 0.83 | ALDH1A1 (0.56) | ALDH1A1LMNAGAAL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073619-A2 | CCR8 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-09-02 | — | — | WO | claimed |
| WO-2004073619-A2 | CCR8 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-09-02 | — | — | WO | disclosed |