Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | CCR2 | P41597 | 4/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.44 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ACLY | P53396 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6923769 | 0.98 | KMT2A (0.47) | KMT2ACCR2KCNH2MEN1ALDH1A1 | |
| SCHEMBL6929374 | 0.95 | KMT2A (0.48) | KMT2ACCR2KCNH2MEN1ALDH1A1 | |
| SCHEMBL3069426 | 0.91 | ALDH1A1 (0.56) | KMT2AMEN1ALDH1A1CYP2C9HPGD | |
| SCHEMBL6924761 | 0.89 | ALDH1A1 (0.55) | KMT2AMEN1ALDH1A1CYP2C9HPGD | |
| SCHEMBL6932063 | 0.87 | LMNA (0.44) | KMT2ACCR2KCNH2ALDH1A1CYP2C9 | |
| SCHEMBL3071070 | 0.86 | HTR7 (0.45) | KMT2AALDH1A1LMNAHPGD | |
| SCHEMBL6928187 | 0.86 | ALDH1A1 (0.58) | KMT2AMEN1ALDH1A1CYP2C9HPGD | |
| SCHEMBL6922856 | 0.85 | ALDH1A1 (0.57) | KMT2AMEN1ALDH1A1LMNA | |
| SCHEMBL6827768 | 0.85 | ALDH1A1 (0.57) | KMT2AMEN1ALDH1A1CYP2C9LMNA | |
| SCHEMBL6830911 | 0.83 | ALDH1A1 (0.56) | KMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004073619-A2 | CCR8 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-09-02 | — | — | WO | claimed |
| WO-2004073619-A2 | CCR8 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-09-02 | — | — | WO | disclosed |