Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.37 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5433897 | 0.89 | MAPK1 (0.40) | MEN1MAPK1KMT2AEPHX2CYP17A1 | |
| SCHEMBL5432061 | 0.85 | MEN1 (0.34) | MEN1MAPK1KMT2AEPHX2HDAC4 | |
| SCHEMBL6810416 | 0.81 | MEN1 (0.41) | MEN1MAPK1KMT2AEPHX2CYP17A1 | |
| SCHEMBL28172595 | 0.79 | MEN1 (0.43) | MEN1MAPK1KMT2AEPHX2CYP17A1 | |
| SCHEMBL5428779 | 0.79 | EPHX2 (0.37) | MEN1MAPK1KMT2AEPHX2 | |
| SCHEMBL26217909 | 0.76 | THRB (0.35) | EPHX2HSD11B1 | |
| SCHEMBL74823 | 0.76 | THRB (0.35) | EPHX2HSD11B1 | |
| SCHEMBL5434102 | 0.75 | EPHX2 (0.38) | MEN1MAPK1KMT2AEPHX2CYP17A1 | |
| Hydrochloric Acid SCHEMBL3683456 | 0.74 | THRB (0.34) | EPHX2HSD11B1ALOX15 | |
| SCHEMBL7744513 | 0.74 | EPHX2 (0.37) | MEN1MAPK1KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6515165-B1 | In a process of the present invention for producing a bridged cyclic polycarboxylic acid t-butyl ester, a bridged cyclic polycarboxylic halide of following Formula to react with a halogenating agent. an adsorption treatment step of subjecting | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2003-02-04 | — | — | US | disclosed |
| EP-1148043-A1 | PROCESS FOR PRODUCING t-BUTYL ESTERS OF BRIDGED-RING POLYCARBOXYLIC ACIDS | Daicel Chemical Industries, Ltd. (JP) | 2001-10-24 | — | — | EP | disclosed |