Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.35 |
| ▸ | F2 | P00734 | 5/20 | 0.34 |
| ▸ | F10 | P00742 | 2/20 | 0.34 |
| ▸ | PLAT | P00750 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.34 |
| ▸ | CTSS | P25774 | 3/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6919834 | 0.88 | ALDH1A1 (0.49) | ALDH1A1GPBAR1F2F10PLAT | |
| SCHEMBL6922998 | 0.84 | ALDH1A1 (0.43) | ALDH1A1F2CTSSCTSL | |
| SCHEMBL6919769 | 0.81 | GPBAR1 (0.36) | GPBAR1F2F10PLATPRSS1 | |
| SCHEMBL6921239 | 0.79 | F2 (0.38) | ALDH1A1GPBAR1F2F10PLAT | |
| SCHEMBL6078342 | 0.79 | F2 (0.43) | ALDH1A1F2KMT2AMEN1 | |
| SCHEMBL6919210 | 0.78 | F2 (0.39) | GPBAR1F2F10PLATPRSS1 | |
| SCHEMBL6919199 | 0.78 | F2 (0.39) | GPBAR1F2F10PLATPRSS1 | |
| SCHEMBL6921204 | 0.78 | F2 (0.40) | ALDH1A1GPBAR1F2F10PLAT | |
| SCHEMBL6917424 | 0.77 | GPBAR1 (0.38) | ALDH1A1GPBAR1F2L3MBTL1KMT2A | |
| SCHEMBL6919762 | 0.77 | F2 (0.38) | ALDH1A1GPBAR1F2F10PLAT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004032834-A2 | THROMBIN INHIBITORS | MERCK & CO., INC. (US) | 2004-04-22 | — | — | WO | disclosed |