Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP7 | Q93009 | 1/20 | 0.35 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | RHEB | Q15382 | 4/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6926697 | 0.77 | USP7 (0.35) | USP7PADI4KDM4ELMNAMAPT | |
| SCHEMBL6929845 | 0.77 | MAPT (0.43) | USP7PADI4KDM4ELMNAMAPT | |
| SCHEMBL6923178 | 0.69 | USP7 (0.37) | USP7PADI4MAPTALDH1A1NPSR1 | |
| SCHEMBL9034679 | 0.66 | — | — | |
| SCHEMBL11125385 | 0.61 | CA2 (0.45) | USP7PADI4KDM4ELMNAMAPT | |
| SCHEMBL24182362 | 0.61 | LMNA (0.38) | KDM4ELMNAMAPTALDH1A1HPGD | |
| SCHEMBL500013 | 0.61 | HTT (0.34) | KDM4ELMNAMAPTALDH1A1HPGD | |
| SCHEMBL30623453 | 0.61 | LMNA (0.38) | KDM4ELMNAMAPTALDH1A1HPGD | |
| SCHEMBL31152111 | 0.61 | HTT (0.34) | KDM4ELMNAMAPTALDH1A1HPGD | |
| SCHEMBL6923956 | 0.60 | USP7 (0.37) | USP7PADI4MAPTALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518268-B1 | Telomerase inhibitors and methods of their use | GERON CORPORATION | 2003-02-11 | — | — | US | disclosed |
| WO-2001002377-A9 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | GERON CORP (US) | 2001-10-11 | — | — | WO | disclosed |
| EP-1109796-A1 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | Geron Corporation (US) | 2001-06-27 | — | — | EP | disclosed |
| WO-2001002377-A1 | TELOMERASE INHIBITORS AND METHODS OF THEIR USE | GERON CORPORATION (US) | 2001-01-11 | — | — | WO | disclosed |