Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 8/20 | 0.54 |
| ▸ | CTSK | P43235 | 7/20 | 0.54 |
| ▸ | CTSB | P07858 | 2/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.49 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 1/20 | 0.47 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.43 |
| ▸ | REN | P00797 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6923147 | 1.00 | CTSS (0.54) | CTSSCTSKCTSBCTSLITGA4 | |
| SCHEMBL6440329 | 0.86 | ITGA4 (0.58) | CTSSCTSKCTSBCTSLITGA4 | |
| SCHEMBL4022463 | 0.86 | ITGA4 (0.58) | CTSSCTSKCTSBCTSLITGA4 | |
| SCHEMBL4022466 | 0.86 | ITGA4 (0.58) | CTSSCTSKCTSBCTSLITGA4 | |
| SCHEMBL2476918 | 0.85 | ACE (0.54) | CTSSCTSKCTSBCTSLITGA4 | |
| SCHEMBL3026223 | 0.85 | ACE (0.54) | CTSSCTSKCTSBCTSLITGA4 | |
| SCHEMBL3268059 | 0.85 | ACE (0.54) | CTSSCTSKCTSBCTSLITGA4 | |
| SCHEMBL4465196 | 0.85 | CTSS (0.74) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL4465200 | 0.85 | CTSS (0.74) | CTSSCTSKCTSBCTSLAKT1 | |
| SCHEMBL13200758 | 0.85 | CTSS (0.48) | CTSSCTSKCTSBCTSLKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518273-B1 | 2-aryl indole derivative as antagonists of tachykinins | MERCK SHARP & DOHME LTD. | 2003-02-11 | — | — | US | disclosed |
| US-6516443-B1 | Error detection convolution code and post processor for correcting dominant error events of a trellis sequence detector in a sampled amplitude read channel for disk storage systems | CIRRUS LOGIC, INCORPORATED | 2003-02-04 | — | — | US | disclosed |
| WO-2000051984-A1 | 2-ARYL INDOLE DERIVATIVES AS ANTAGONISTS OF TACHYKININS | MERCK SHARP & DOHME LIMITED (GB) | 2000-09-08 | — | — | WO | disclosed |