SCHEMBL6923219

SCHEMBL6923219

O=C1CCC=C1c1ccccc1[N+](=O)[O-]

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 1/20 0.51
ALDH1A1 P00352 4/20 0.49
TDP1 Q9NUW8 1/20 0.49
MAPT P10636 2/20 0.46
KMT2A Q03164 2/20 0.46
RECQL P46063 1/20 0.46
MCL1 Q07820 1/20 0.46
RXFP1 Q9HBX9 1/20 0.46
S100A4 P26447 2/20 0.44
PTPRC P08575 1/20 0.44
HSD17B10 Q99714 2/20 0.41
TP53 P04637 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2D6 P10635 1/20 0.41
CYP2C9 P11712 1/20 0.41
MAPK1 P28482 1/20 0.41
CYP2C19 P33261 1/20 0.41
STAT6 P42226 1/20 0.41
HIF1A Q16665 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6823018 0.90 PTPN1 (0.49) PTPN1ALDH1A1TDP1MAPTKMT2A
SCHEMBL6822719 0.89 PTPN1 (0.48) PTPN1ALDH1A1TDP1MAPTKMT2A
SCHEMBL30535903 0.73 ALDH1A1 (0.74) PTPN1ALDH1A1TDP1KMT2ARECQL
SCHEMBL1287837 0.73 ALDH1A1 (0.74) PTPN1ALDH1A1TDP1KMT2ARECQL
SCHEMBL8993582 0.72 ALDH1A1 (0.61) PTPN1ALDH1A1TDP1MAPTKMT2A
SCHEMBL17449581 0.72 ALDH1A1 (0.48) PTPN1ALDH1A1TDP1MAPTKMT2A
SCHEMBL12365077 0.71 SRD5A2 (0.45) ALDH1A1TDP1MAPTKMT2ALMNA
SCHEMBL29337140 0.71 ALDH1A1 (0.71) PTPN1ALDH1A1TDP1KMT2AS100A4
SCHEMBL30987815 0.71 ALDH1A1 (0.71) PTPN1ALDH1A1TDP1KMT2AS100A4
Ammonia Solution, Strong SCHEMBL9060371 0.71 ALDH1A1 (0.71) PTPN1ALDH1A1TDP1KMT2AS100A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004096766-A1 A METHOD OF INDOLE SYNTHESIS THE AUSTRALIAN NATIONAL UNIVERSITY (AU) 2004-11-11 WO disclosed